Urine Cortisol:Creatinine Ratio to Diagnose Hypoadrenocorticism in Dogs

Kylie Grady, DVM, North Carolina State University

Adam J. Birkenheuer, DVM, PhD, DACVIM, North Carolina State University

ArticleLast Updated March 20233 min read
Gloved hand holding up a urine sample.

In the Literature

Moya MV, Refsal KR, Langlois DK. Investigation of the urine cortisol to creatinine ratio for the diagnosis of hypoadrenocorticism in dogs. J Am Vet Med Assoc. 2022;260(9):1041-1047. doi:10.2460/javma.21.12.0538


The Research …

Naturally occurring hypoadrenocorticism is an endocrine disorder characterized by a deficiency in glucocorticoids and/or mineralocorticoids that can lead to life-threatening clinical and biochemical abnormalities.1 Timely and accurate diagnosis is critical.  

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