Oxygen Reserve Index May Hasten Deoxygenation Detection

ArticleLast Updated July 20241 min read
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Zanusso F, De Benedictis GM, Bellini L. Exploring oxygen reserve index for timely detection of deoxygenation in canine patients recovering from anesthesia. Res Vet Sci. 2024;173:105268. doi:10.1016/j.rvsc.2024.105268


Research Note

Pulse oximetry is a noninvasive, user-friendly method for estimating arterial partial pressure of oxygen (PaO2); however, decreased values are only displayed when PaO2 is <80 mm Hg, which may delay detection of impending arterial oxygen decreases. The oxygen reserve index (ORi) is a dimensionless index ranging from 0 (ie, no reserve, PaO2 <100 mm Hg) to 1 (ie, high reserve, PaO2 >200 mm Hg) and is a reliable trending variable in dogs and humans (relative changes in ORi predict consistent changes in PaO2 with good sensitivity).

In this prospective study, ORi and oxygen saturation (SpO2) were monitored when dogs (n = 51) were disconnected from a ventilator 10 minutes after elective surgery was performed with the patient under general anesthesia. ORi decreased before SpO2, with a median time of 30 to 35 seconds from ORi of 0.5 to SpO2 of 95%. More rapid detection of deoxygenation may facilitate timely intervention.