Reference values for ultrasonographic pancreatic size and the appearance of the pancreatic duct have been reported for cats, but limited data are available for dogs. This study described the ultrasonographic appearance and size of the pancreas and pancreatic duct in dogs (n = 242) with no clinical evidence of GI disease. Pancreatic thickness ranged from 3.5–16 mm, with a reference value of ~1 cm in medium-sized dogs (15–30 kg of body weight). Mean pancreatic duct diameter in medium-sized dogs was 0.8 mm; range in all dogs was 0.1–1.2 mm. The right and left pancreatic ducts were visible in 88% and 16.9% of dogs, respectively. The body was visible in only 6.6% of dogs. Although positive correlations were found between body weight and pancreatic duct diameter, no significant correlations were found between age and pancreatic thickness or pancreatic duct diameter. These values may be useful for assessing pancreatic abnormalities (eg, chronic pancreatitis, exocrine pancreatic insufficiency).