Clindamycin

Melissa Clark, DVM, PhD, DACVCP, DACVIM, Gulf Coast Veterinary Specialists, Houston, Texas

ArticleLast Updated May 20153 min readPeer Reviewed
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Clindamycin is an orally bioavailable antibiotic effective against many infections in dogs and cats.

Clinical Applications

Clindamycin, a lincosamide antibiotic, is labeled for oral treatment of bacterial infections of the skin, soft tissue, periodontal tissue, and bone.

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  • Dogs & cats: Dental and soft tissue infections; skin infections (wounds and abscesses) caused by susceptible organisms

    • Dogs: 5.5–33 mg/kg PO q12h1

    • Cats: 11–33 mg/kg PO q24h1

  • Dogs only: Osteomyelitis

    • 11–33 mg/kg PO q12h1 

      • In one study of canine posttraumatic osteomyelitis, 11 mg/kg q12h appeared more effective than a lower dose of 5.5 mg/kg q12h.2 

      • In a more recent study, in vitro resistance was documented in 59% of organisms cultured from dogs with osteomyelitis (predominantly posttraumatic and staphylococcal).3

Clindamycin is also used for treatment of toxoplasmosis in cats.

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