Clindamycin
Melissa Clark, DVM, PhD, DACVCP, DACVIM, Gulf Coast Veterinary Specialists, Houston, Texas
Clindamycin is an orally bioavailable antibiotic effective against many infections in dogs and cats.
Clinical Applications
Clindamycin, a lincosamide antibiotic, is labeled for oral treatment of bacterial infections of the skin, soft tissue, periodontal tissue, and bone.
Dogs & cats: Dental and soft tissue infections; skin infections (wounds and abscesses) caused by susceptible organisms
Dogs: 5.5–33 mg/kg PO q12h1
Cats: 11–33 mg/kg PO q24h1
Dogs only: Osteomyelitis
11–33 mg/kg PO q12h1
In one study of canine posttraumatic osteomyelitis, 11 mg/kg q12h appeared more effective than a lower dose of 5.5 mg/kg q12h.2
In a more recent study, in vitro resistance was documented in 59% of organisms cultured from dogs with osteomyelitis (predominantly posttraumatic and staphylococcal).3
Clindamycin is also used for treatment of toxoplasmosis in cats.
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