Research Note: Intralymphatic Immunotherapy in the Treatment of Canine Atopic Dermatitis

Sign in to Print/View PDF

The study authors hypothesized that intralymphatic immunotherapy induces a better, more rapid response than do other types of immunotherapy for treating canine atopic dermatitis. Alum-precipitated allergen extract was injected into the popliteal lymph nodes of 51 participants. Twenty-two dogs completed the study and were included in a per-protocol analysis of results; all 51 participants were included in a separate intention-to-treat analysis. Pruritus and quality-of-life scores improved significantly in the intention-to-treat analysis; however, Canine Atopic Dermatitis Extent and Severity Index (CADESI) scores showed significant improvement only in the per-protocol analysis. Given the limited adverse effects, evaluation of intralymphatic immunotherapy as a safe, feasible, long-lasting treatment for canine atopic dermatitis is warranted.

Source

Material from Clinician’s Brief may not be reproduced, distributed, or used in whole or in part without prior permission of Educational Concepts, LLC. For questions or inquiries please contact us.

Practice Tools

Topic

Dermatology

Clinician's Brief provides relevant diagnostic and treatment information for small animal practitioners. It has been ranked the #1 most essential publication by small animal veterinarians for 9 years.*

*2007-2017 PERQ and Essential Media Studies

© 2018 Educational Concepts, L.L.C. dba Brief Media ™ All Rights Reserved. Privacy Policy (Updated 05/08/2018) Terms of Use (Updated 05/08/2018)